A Contemporary, Population-Based Study of Lymphedema Risk Factors in Older Breast Cancer Women

نویسندگان

  • Tina W. F. Yen
  • Xiaolin Fan
  • Rodney Sparapani
  • Purushuttom W. Laud
  • Alonzo P. Walker
  • Ann B. Nattinger
چکیده

BACKGROUND: We studied potential risk factors for lymphedema in a contemporary population of older breast cancer patients. METHODS: Telephone surveys were conducted among women (65-89 years) identified from Medicare claims as having initial breast cancer surgery in 2003. Lymphedema was classified by self-report. Surgery and pathology information was obtained from Medicare claims and the state cancer registries. RESULTS: Of 1,338 patients treated by 707 surgeons, 24% underwent sentinel lymph node biopsy (SLNB) and 57% axillary lymph node dissection (ALND). At a median of 48 months postoperatively, 193 (14.4%) had lymphedema. Lymphedema developed in 7% of the 319 patients who underwent SLNB and 21% of the 759 patients who underwent ALND. When controlling for patient age, tumor size, type of breast cancer, type of breast and axillary surgery, receipt of radiation, chemotherapy, and hormonal therapy, and surgeon case volume, the independent predictors of lymphedema were the removal of more than five lymph nodes (OR 4.68-5.61, 95% CI: 1.36-19.74 for 6-15 nodes; OR 10.50, 95% CI 2.88-38.32 for > 15 nodes) and the presence of lymph node metastases (OR 1.98, 95% CI 1.21-3.24). CONCLUSIONS: Four years postoperatively, 14% of a contemporary, population-based cohort of elderly breast cancer survivors have self-reported lymphedema. In this group of predominately community-based surgeons, the number of lymph nodes removed is more predictive of lymphedema rather than whether SLNB or ALND was performed. As more women with breast cancer undergo only SLNB, it is essential that they still be counseled on their risk for lymphedema.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The prediction of lymphedema via the combination of the selected data mining algorithms

Background: Breast cancer is the second leading cause of cancer death in women, after lung cancer. Due to the importance of predicting this disease, the use of data mining methods in medical research is more significant than before. Data mining algorithms can be a great help in preventing the development of lymphedema in patients. The aim Of this study was to create a diagnosis system that can ...

متن کامل

The effect of Combined Decongestive Therapy and pneumatic compression pump on body image in women with breast cancer related lymphedema

Introduction: Patients with breast cancer who have two positive axillary lymph nodes, along with mastectomy, they undergo axillary node dissection. Lymphedema after axillary surgery is a feared complication. This women experience pain and body image impairments. Any intervention to reduce lymphedema, affects the body image of these patients. Method: This study is a randomized, single-blind clin...

متن کامل

Older breast cancer survivors: factors associated with self-reported symptoms of persistent lymphedema over 7 years of follow-up.

Lymphedema of the arm is a common complication of breast cancer with symptoms that can persist over long periods of time. For older women (over 50% of breast cancer cases) it means living with the potential for long-term complications of persistent lymphedema in conjunction with the common diseases and disabilities of aging over survivorship. We identified women > or =65 years diagnosed with pr...

متن کامل

Breast cancer risk assessment in Iranian women by Gail model

  Abstract   Background: Due to the high incidence of breast cancer and the effect of its early   diagnosis on decreasing morbidity and mortality, we used the Gail model to study   breast cancer risk in Iranian women.   Methods: This study was done in a simple randomized way. Participants were 2000   Iranian women older than 35 years old. The questionnaire consisted of demographic   data such a...

متن کامل

بررسی عوامل خطر ابتلا به سرطان پستان

Introduction: Breast cancer is one the most common form of cancer in women all over the world. The incidence of women breast cancer is increasing in Iran. There are many risk factors involved in the risk of breast cancer so that these risk factors have been determined based on genetic, environmental, and geographical conditions in various studies. The current study aimed to evaluate the risk fa...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2010